TY - JOUR AU - Mani, Sandeep AU - Lakshmanan, Archana AU - Subramanyan, Annapurneswari PY - 2022/03/31 TI - Pituicytoma- Case Report Of A Rare Sellar/ Suprasellar Mass JF - Diagnostic Pathology; Vol 7 No 1 (2022): Vol 7 No 1DO - 10.17629/www.diagnosticpathology.eu-2022-7:284 KW - N2 - Background: Pituicytoma is a rare primary tumor of the sellar and suprasellar region, arising from the pituicytes which are specialized glial cells in the neurohyphophysis and infundibulum.   Objective: Radiological features being non- specific, histopathological examination and immunohistochemistry will help us in arriving at the correct diagnosis. Material and methods: We report a case of pituicytoma in a 48 year old woman arising in the sellar/suprasellar region. Results: Histopathological examination of the lesion showed elongate bipolar spindle cells arranged in fascicular and storiform pattern. The neoplastic cells were diffusely positive for TTF-1, S-100, vimentin, variably positive for GFAP, negative for synaptophysin and Ki-67 index was less than one percentage. Conclusion: Pituicytomas are rare tumors of the sellar and suprasellar region and its diagnosis is typically based on histopathological examination with a varied immunohistochemical profiles but with consistent TTF-1 positivity. UR - http://www.diagnosticpathology.eu/content/index.php/dpath/article/view/284