Low Grade Well-circumscribed Well Differentiated Liposarcoma Developed in Fibroadenoma with Stromal adipose differentiation of the Breast; A Case Report

  • Essam Ayad Cairo University + Italian Hospital - Cairo


Fibroadenomas are the most common breast tumor in adolescents and young women.They comprise  20% of benign breast masses and 12% of all breast masses in postmenopausal women. Smooth muscle metaplasia and adipose differentiation are uncommon forms of stromal differentiation encountered in a minority of fibroadenomas. Liposarcoma can arise from pre-existing benign lesions like phylloides tumour or from lipoid tissue in the breast. In this article we present a case of 38 year-old female who presented with a right breast mass which was clinically diagnosed as a case of fibroadenoma, but histologically showed a low grade well-circumscribed liposarcoma discovered in a pericanalicular type of fibroadenoma with stromal adipose differentiation. According to our knowledge, this the first case of a well-circumscribed liposarcoma arises in fibroadenoma of the breast.


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How to Cite
AYAD, Essam. Low Grade Well-circumscribed Well Differentiated Liposarcoma Developed in Fibroadenoma with Stromal adipose differentiation of the Breast; A Case Report. Diagnostic Pathology, [S.l.], v. 2, n. 1, feb. 2016. ISSN 2364-4893. Available at: <http://www.diagnosticpathology.eu/content/index.php/dpath/article/view/100>. Date accessed: 21 feb. 2024. doi: https://doi.org/10.17629/www.diagnosticpathology.eu-2016-2:100.
Case Report


Breast Fibroadenoma; Stromal Adipose differentiation; Well-differentiated liposarcoma.