Pituicytoma- Case Report Of A Rare Sellar/ Suprasellar Mass

  • Sandeep Mani Apollo Hospitals
  • Archana Lakshmanan Apollo cancer centre, Chennai
  • Annapurneswari Subramanyan Apollo cancer centre, Chennai

Abstract

Background: Pituicytoma is a rare primary tumor of the sellar and suprasellar region, arising from the pituicytes which are specialized glial cells in the neurohyphophysis and infundibulum.  


Objective: Radiological features being non- specific, histopathological examination and immunohistochemistry will help us in arriving at the correct diagnosis.


Material and methods: We report a case of pituicytoma in a 48 year old woman arising in the sellar/suprasellar region.


Results: Histopathological examination of the lesion showed elongate bipolar spindle cells arranged in fascicular and storiform pattern. The neoplastic cells were diffusely positive for TTF-1, S-100, vimentin, variably positive for GFAP, negative for synaptophysin and Ki-67 index was less than one percentage.


Conclusion: Pituicytomas are rare tumors of the sellar and suprasellar region and its diagnosis is typically based on histopathological examination with a varied immunohistochemical profiles but with consistent TTF-1 positivity.

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Author Biographies

Archana Lakshmanan, Apollo cancer centre, Chennai

Consultant pathologist,

Apollo cancer centre, Chennai.

Annapurneswari Subramanyan, Apollo cancer centre, Chennai

Chief of surgical pathology,

Apollo cancer centre, Chennai

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Published
2022-03-31
How to Cite
MANI, Sandeep; LAKSHMANAN, Archana; SUBRAMANYAN, Annapurneswari. Pituicytoma- Case Report Of A Rare Sellar/ Suprasellar Mass. Diagnostic Pathology, [S.l.], v. 7, n. 1, mar. 2022. ISSN 2364-4893. Available at: <http://www.diagnosticpathology.eu/content/index.php/dpath/article/view/284>. Date accessed: 28 may 2022. doi: https://doi.org/10.17629/www.diagnosticpathology.eu-2022-7:284.
Section
Case Report