Mucous gland adenoma of a segment bronchus - Case report

  • Zaklina Zarko Mijovic Medical Faculty, University of Nis
  • Dragan Mihailovic Medical Faculty, University of Nis
  • Nikola Zivkovic Medical Faculty, University of Nis
  • Milos Stankovic Medical Faculty, University of Nis
  • Milos Kostov Medical Faculty, University of Nis

Abstract

Background

Mucous gland adenoma of the bronchus is a rare benign epithelial tumor. The majority arises from the submucosal seromucous glands and ducts of the proximal airways. In bronchus biopsy specimen it might be difficult to distinguish mucous gland adenomas from low-grade malignant tumors, such as carcinoids, mucoepidermoid carcinomas, or adenoid cystic carcinomas. Complete tumor resection serves for both definite diagnosis and potential curative treatment.

Case

A non smoking man of 78 years suffered from cough, dyspnea and recently from hemoptysis. Fiberoptic bronchoscopy revealed a polypoid, well-circumscribed mass in the right posterior segmental bronchus. A bronchoscopic tumor excision was performed.

Histology and immunohistochemistry (IHC)

The tumor displayed with exuberant dilated cystic glands lined by columnar, cuboidal or flattened mucus secreting cells. IHC was positive for EMA, CKAE1/AE3, and negative for TTF1.

Conclusion

Uncommon benign bronchus adenomas should be taken into account in addition to the common malignant lung carcinomas with endobronchial growth pattern. Endoscopic tumor excision of bronchus adenomas is indicated for potential curative treatment, especially in patients of higher age.

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Published
2015-04-07
How to Cite
MIJOVIC, Zaklina Zarko et al. Mucous gland adenoma of a segment bronchus - Case report. Diagnostic Pathology, [S.l.], apr. 2015. ISSN 2364-4893. Available at: <http://www.diagnosticpathology.eu/content/index.php/dpath/article/view/8>. Date accessed: 26 nov. 2020. doi: https://doi.org/10.17629/www.diagnosticpathology.eu-2015-1:8.
Issue
Section
Case Report

Keywords

Bronchus adenoma; endoscopy; immunohistochemistry; video-assisted thoracic surgery; prognosis