Mucous gland adenoma of a segment bronchus - Case report
Abstract
Background
Mucous gland adenoma of the bronchus is a rare benign epithelial tumor. The majority arises from the submucosal seromucous glands and ducts of the proximal airways. In bronchus biopsy specimen it might be difficult to distinguish mucous gland adenomas from low-grade malignant tumors, such as carcinoids, mucoepidermoid carcinomas, or adenoid cystic carcinomas. Complete tumor resection serves for both definite diagnosis and potential curative treatment.
Case
A non smoking man of 78 years suffered from cough, dyspnea and recently from hemoptysis. Fiberoptic bronchoscopy revealed a polypoid, well-circumscribed mass in the right posterior segmental bronchus. A bronchoscopic tumor excision was performed.
Histology and immunohistochemistry (IHC)
The tumor displayed with exuberant dilated cystic glands lined by columnar, cuboidal or flattened mucus secreting cells. IHC was positive for EMA, CKAE1/AE3, and negative for TTF1.
Conclusion
Uncommon benign bronchus adenomas should be taken into account in addition to the common malignant lung carcinomas with endobronchial growth pattern. Endoscopic tumor excision of bronchus adenomas is indicated for potential curative treatment, especially in patients of higher age.
Keywords
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DOI: http://dx.doi.org/10.17629/www.diagnosticpathology.eu-2015-1:8
Copyright (c) 2015 Zaklina Zarko Mijovic
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