How do I diagnose Pagetoid Bowen Disease
Abstract
Bowen disease is a variant of squamous carcinoma in situ, which sometimes presents with a pagetoid growth pattern with cytologically atypical clear cells. In that case, the differencial diagnosis includes Paget disease and melanoma in situ, as well as less common entities. Here we describe a case where histological differenciation is difficult and immunohistochemical studies are necessary to make a diagnosis. Here we also highlight the heterogeneity of CK7 expression and the apparent specific expression of p63 in Pagetoid Bowen Disease.
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References
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DOI: http://dx.doi.org/10.17629/www.diagnosticpathology.eu-2015-1:88
Copyright (c) 2015 Rita do EspÃrito Santo Carvalho
This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.
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