Pituicytoma- Case Report Of A Rare Sellar/ Suprasellar Mass
Background: Pituicytoma is a rare primary tumor of the sellar and suprasellar region, arising from the pituicytes which are specialized glial cells in the neurohyphophysis and infundibulum.
Objective: Radiological features being non- specific, histopathological examination and immunohistochemistry will help us in arriving at the correct diagnosis.
Material and methods: We report a case of pituicytoma in a 48 year old woman arising in the sellar/suprasellar region.
Results: Histopathological examination of the lesion showed elongate bipolar spindle cells arranged in fascicular and storiform pattern. The neoplastic cells were diffusely positive for TTF-1, S-100, vimentin, variably positive for GFAP, negative for synaptophysin and Ki-67 index was less than one percentage.
Conclusion: Pituicytomas are rare tumors of the sellar and suprasellar region and its diagnosis is typically based on histopathological examination with a varied immunohistochemical profiles but with consistent TTF-1 positivity.
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